Investigating gene expression and mapping in cancer using advanced imaging techniques
DMS/NIGMS 1: Topological Study on Histological Images and Spatial Transcriptomics
This study is looking at how genes behave in breast and brain cancers by using advanced imaging techniques, which could help doctors understand tumors better and improve treatments for patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University New York Stony Brook NIH-funded |
| Lab location | 1 site (Stony Brook, United States) |
| Project ID | NIH-11100515 on NIH RePORTER |
What this research studies
This research focuses on enhancing the understanding of gene expression in breast and brain cancers through advanced imaging techniques. By integrating deep learning with topological analysis of histological images, the project aims to create more accurate representations of spatial transcriptomics data. Patients' tumor samples will be analyzed to identify gene localization and expression patterns, which could lead to better diagnostic and treatment strategies. The study will utilize both public and proprietary data to ensure comprehensive results.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with breast cancer, particularly triple-negative breast cancer, or brain cancer.
Not a fit: Patients with non-malignant tumors or those not diagnosed with breast or brain cancers may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and targeted therapies for patients with breast and brain cancers.
How similar studies have performed: Other research has shown promise in using deep learning and topological methods for analyzing cancer data, indicating a potential for success in this approach.
Where this research is happening
Stony Brook, United States
- State University New York Stony Brook — Stony Brook, United States (Active)
Researchers
- Principal investigator: Chen, Chao — State University New York Stony Brook
- Study coordinator: Chen, Chao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.