Investigating cognitive decline and dementia in older Kerala Americans
Cognitive decline and dementia in older Kerala Americans
This study is looking at how common mild cognitive impairment and Alzheimer’s disease are among older immigrants from Kerala, India, living in the U.S., and it aims to find out what factors might help protect their brain health or put them at risk, so if you're an older adult from Kerala, you could help us learn more about this important issue!
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-11081696 on NIH RePORTER |
What this research studies
This research focuses on understanding the incidence of mild cognitive impairment and Alzheimer’s disease among older first-generation immigrants from Kerala, India, living in the U.S. The study will involve clinically and biologically assessing 400 older adults to identify risk and protective factors related to Alzheimer’s disease and related dementias. By comparing this group with a cohort from Kerala, the research aims to uncover how sociocultural factors influence cognitive health in immigrant populations. Participants will undergo various assessments to gather data on their cognitive health and biological markers.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults aged 65 and above who are first-generation immigrants from Kerala, India.
Not a fit: Patients who are not of Kerala descent or who are younger than 65 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and potential interventions for cognitive decline in older Kerala Americans.
How similar studies have performed: This research is novel as there are few studies specifically examining Alzheimer’s disease in immigrant populations like Kerala Americans.
Where this research is happening
Bronx, United States
- Albert Einstein College of Medicine — Bronx, United States (Active)
Researchers
- Principal investigator: Verghese, Joe — Albert Einstein College of Medicine
- Study coordinator: Verghese, Joe
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.