Investigating cancer cell epigenomes and transcriptomes
Official title: Epigenomics Core
Funded at Dana-Farber Cancer Inst · NIH-11016332 · Data updated 2026-11-12
This study is looking at the tiny changes in cancer cells to learn more about how they work, which could help find new ways to treat cancer.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dana-Farber Cancer Inst NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | April 1, 2025 |
| Project end | March 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $394,295 |
| NIH project number | 1P01CA295524-01 |
| Project ID | NIH-11016332 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with various types of cancer who are interested in understanding the genetic and epigenetic factors influencing their disease.
✕Less likely to help
Patients with non-cancerous conditions or those not interested in genetic profiling may not receive any benefit from this research.
What this research studies
This research focuses on analyzing the epigenetic and transcriptomic profiles of cancer cells using advanced genome-wide profiling techniques. By employing assays like ATAC sequencing, the project aims to uncover critical biological information at both bulk and single-cell levels. The Epigenomics Core will provide essential support to various cancer research projects by integrating data and applying sophisticated analysis methods to distinguish meaningful signals from background noise. This approach could lead to a better understanding of cancer biology and potential therapeutic targets.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of cancer mechanisms and lead to improved treatment strategies.
How similar studies have gone: Previous research utilizing similar epigenomic profiling techniques has shown promising results in understanding cancer biology and identifying potential therapeutic targets.
Where this research is happening
-
Dana-Farber Cancer Inst
Boston, United States Active
Researchers
- Principal investigator: Long, Henry W. — Dana-Farber Cancer Inst
- Study coordinator: Long, Henry W.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.