Investigating brain chemistry using advanced imaging techniques
Official title: Downfield MR spectroscopic imaging of the human brain
Funded at Johns Hopkins University · NIH-10841623 · Data updated 2026-11-12
This study is working on new ways to take detailed pictures of brain chemistry to help doctors better understand and treat brain conditions, so patients can have more accurate diagnoses and improved treatment options.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | June 1, 2023 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $136,231 |
| NIH project number | 5K99EB034768-02 |
| Project ID | NIH-10841623 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include adults aged 21 and older who are experiencing neurological symptoms or have been diagnosed with brain tumors.
✕Less likely to help
Patients with conditions unrelated to brain chemistry or those under 21 years old may not receive benefits from this research.
What this research studies
This research focuses on developing advanced imaging techniques to analyze brain chemistry through downfield magnetic resonance spectroscopic imaging (DF-MRSI). The approach involves creating optimized 3D imaging methods that can capture detailed chemical signals from the brain, which may provide insights into various neurological conditions. By utilizing high-field MRI systems, the study aims to enhance the sensitivity and accuracy of brain imaging, ultimately leading to better diagnostic tools. Patients may benefit from improved understanding and treatment options for brain-related conditions.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and targeted treatments for brain tumors and other neurological disorders.
How similar studies have gone: Previous studies have shown promise in using advanced MRI techniques for brain imaging, but this specific approach to downfield MRSI is relatively novel.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Özdemir, İpek — Johns Hopkins University
- Study coordinator: Özdemir, İpek
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.