InSTagrAn: At-home PrEP adherence support with telehealth for MSM who use meth
Official title: InSTagrAn: A Scalable Telehealth and Urine Tenofovir Self-Testing Intervention to Enhance PrEP Adherence Among People Who Use Methamphetamine
Funded at Graduate School of Public Health and Health Policy · NIH-11328377 · Data updated 2026-11-12
A scalable program that combines at-home urine testing for PrEP adherence with remote counseling to help HIV-negative MSM who use methamphetamine stay adherent to PrEP.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Graduate School of Public Health and Health Policy NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | June 15, 2026 |
| Project end | March 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $644,212 |
| NIH project number | 1R01DA065479-01 |
| Project ID | NIH-11328377 on NIH RePORTER |
Who could benefit from this research
✓Could help
HIV-negative men who have sex with men, use methamphetamine, and report suboptimal PrEP adherence.
✕Less likely to help
People not using PrEP or without methamphetamine use may not benefit.
What this research studies
If you are a man who has sex with men and uses methamphetamine, this program offers an at-home urine test for HIV prevention medication and telehealth coaching to help you stay adherent to PrEP. Participants will receive monthly self-administered tests and two online counseling sessions each month to address barriers and keep you on track. The goal is to make PrEP easier, private, and more reliable so you can reduce your HIV risk in daily life.
Why it matters
Potential benefit: If successful, this program could improve PrEP adherence and lower HIV risk for MSM who use methamphetamine.
How similar studies have gone: Preliminary data from similar interventions show feasibility and potential adherence improvements, with room for validation in a larger trial.
Where this research is happening
-
Graduate School of Public Health and Health Policy
New York, United States Active
Researchers
- Principal investigator: Grov, Christian — Graduate School of Public Health and Health Policy
- Study coordinator: Grov, Christian
Related research
Other NIH-funded projects on the same topics.
-
mChoice: Boosting PrEP Use and Adherence for Black and Latino MSM with Tailored Training and Support
A national study to help Black and Latino men who have sex with men start and stick with PrEP through culturally matched provider training and patient support.
-
Harnessing male peer networks to boost HIV testing and PrEP use
A large clinical trial in South Africa tests whether giving HIV self-test kits through male peer networks, with phone support, increases PrEP uptake among men.
-
Harnessing men's peer networks to boost HIV self-testing and PrEP use
A large project in South Africa tests whether giving HIV self-test kits through men’s social networks, with phone support, can lead to more men starting PrEP and using HIV testing.
-
Participatory system dynamics to improve PrEP access in the Bronx
A community-driven project in the Bronx will use system dynamics to identify practical ways to help people at risk for HIV start and stay on PrEP.
-
TB PrEP: Bringing HIV prevention to households affected by TB in Uganda
Aims to help people in households with TB in Uganda access HIV PrEP as part of a combined prevention approach.
-
CARES: A practical program to help adolescent girls and young women use PrEP in Africa
A program called CARES helps young women in South Africa and Zimbabwe use different PrEP options better, with counseling, reminders, and options for support.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.