Innovative models to study kidney function and disease
Official title: Model Systems Core
Funded at University of Pittsburgh at Pittsburgh · NIH-10914932 · Data updated 2026-11-12
This study is all about creating new ways to learn more about how kidneys work and what happens when they get sick, using everything from tiny yeast to more complex animals, so that researchers can find better treatments for kidney problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | September 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $295,856 |
| NIH project number | 5U54DK137329-02 |
| Project ID | NIH-10914932 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with kidney-related conditions or those interested in kidney health.
✕Less likely to help
Patients with conditions unrelated to kidney function or those not residing in the research location may not receive benefit from this research.
What this research studies
This research focuses on developing a variety of innovative model systems to enhance understanding of kidney physiology and pathophysiology. It utilizes simple organisms like yeast and complex animal models to explore kidney development, function, and responses to injury in both healthy and diseased states. The project is structured into three subcores, each providing unique tools and resources for kidney researchers, including human kidney organoids and rodent models. By leveraging these diverse models, the research aims to facilitate breakthroughs in kidney health and disease treatment.
Why it matters
Potential benefit: If successful, this research could lead to significant advancements in the understanding and treatment of kidney diseases.
How similar studies have gone: Other research utilizing innovative model systems has shown promise in advancing our understanding of kidney diseases, indicating a strong potential for success in this approach.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Subramanya, Arohan R — University of Pittsburgh at Pittsburgh
- Study coordinator: Subramanya, Arohan R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.