Infertility and long-term health in Hispanic women with Mexican heritage
Official title: Infertility and Long-Term Health Outcomes Among Hispanic Women with Mexican Heritage
Funded at University of Arizona · NIH-11387558 · Data updated 2026-11-12
A large study will follow Hispanic women with Mexican heritage to understand how infertility relates to cancer, diabetes, and heart-related illnesses over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | August 22, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $436,802 |
| NIH project number | 5R01HD114871-03 |
| Project ID | NIH-11387558 on NIH RePORTER |
Who could benefit from this research
✓Could help
Hispanic women with Mexican heritage who are part of or can contribute to the Mexican Teachers’ Cohort and have fertility histories.
✕Less likely to help
The study may offer limited direct benefit to individuals who are not at risk of infertility or who are not part of the cohort.
What this research studies
This project uses data from the Mexican Teachers’ Cohort to examine how infertility diagnoses and treatments relate to long-term health outcomes such as breast cancer, diabetes, and cardiometabolic diseases. Researchers will analyze years of reproductive and health information to identify patterns and risks. The goal is to better understand whether infertility experiences influence future health in this population and what factors might modify those risks.
Why it matters
Potential benefit: It could lead to tailored health guidance and later-life cancer and chronic disease prevention for Hispanic women with infertility histories.
How similar studies have gone: Prior work suggests infertility history may be linked to higher risks of certain cancers and cardiometabolic diseases, but data in Mexican heritage populations are limited.
Where this research is happening
-
University of Arizona
Tucson, United States Active
Researchers
- Principal investigator: Farland, Leslie V — University of Arizona
- Study coordinator: Farland, Leslie V
Related research
Other NIH-funded projects on the same topics.
-
Molecular clues to endometriosis-related infertility
This grant explores how molecular changes in endometriosis contribute to infertility, with the aim of finding better ways to diagnose and treat the condition.
-
Oral FSH receptor activator drugs to lower infertility treatment costs
A new oral drug approach aims to improve fertility treatments by using a small molecule that activates the FSH receptor, potentially making infertility care more affordable.
-
Prediction of ART outcomes for male factor infertility using single-molecule chromatin stenciling in sperm
A new test called sperm Fiber-seq is being developed to better predict how well ART will work for couples dealing with male-factor infertility.
-
TLR4 blocker for improving fertility in PCOS
A promising, already-approved drug (disulfiram) will be tested to see if it can reduce inflammation and improve ovulation in women with PCOS.
-
Innovative 3D-printed vaginal ring for progesterone delivery to support IVF pregnancies
A new 3D-printed vaginal ring delivers progesterone over 28 days for IVF patients, aiming to improve pregnancy success with fewer rings and less frequent dosing.
-
Genetics of Male Infertility: Accelerating Discovery and Clinical Impact
This grant aims to uncover the genetic causes of male infertility (azoospermia) to improve diagnosis and pave the way for personalized treatments.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.