Increasing uptake of long-acting HIV prevention and treatment among Black and Latinx men with suboptimal adherence in Southern California
Official title: Developing Status-Neutral Approaches to Increase Uptake of Long Acting Injectable PrEP and ART Among Black and Latinx Men with Less Than Optimal Adherence in Southern California
Funded at University of California, San Diego · NIH-11257130 · Data updated 2026-11-12
A study to understand barriers and create new ways to help Black and Latinx men ages 18-45 use long-acting HIV prevention and treatment options in Southern California.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | July 15, 2026 |
| Project end | July 14, 2028 |
| Funding year | 2026 |
| Award (this year) | $441,215 |
| NIH project number | 1R21MH139447-01A1 |
| Project ID | NIH-11257130 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal participants are Black and Latinx men who have sex with men, aged 18-45, with suboptimal engagement in HIV care or prevention in the specified Southern California counties.
✕Less likely to help
Individuals who are not in the target demographic or who are already fully adherent to all HIV prevention and treatment regimens may see limited direct benefit.
What this research studies
This project focuses on Black and Latinx sexual minority men in three Southern California counties who struggle with engagement in HIV care or prevention. It will identify what makes it hard or easy to start and stick with long-acting PrEP and ART, and test new approaches to increase use and persistence. The work combines community input, targeted outreach, and pilot strategies to improve adherence and viral suppression with long-acting options. The study is led by UC San Diego and aims to generate practical steps that clinics and communities can adopt. Results could inform broader efforts to reduce HIV disparities and improve health outcomes in this population.
Why it matters
Potential benefit: If successful, the project could help more Black and Latinx men maintain long-acting HIV prevention and treatment, leading to better health and fewer new infections.
How similar studies have gone: Prior work has shown that long-acting HIV prevention and treatment can improve adherence, but barriers among Black and Latinx men in this region require targeted, community-informed approaches.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Campbell, Chadwick Karl — University of California, San Diego
- Study coordinator: Campbell, Chadwick Karl
Related research
Other NIH-funded projects on the same topics.
-
Pharmacy-enabled rapid HIV prevention and treatment access in Southern communities
A quick, pharmacy-based program in Alabama aims to make HIV testing and rapid ARV/PrEP access available in community pharmacies to help people in high-burden areas get connected to care fast.
-
mChoice: Boosting PrEP Use and Adherence for Black and Latino MSM with Tailored Training and Support
A national study to help Black and Latino men who have sex with men start and stick with PrEP through culturally matched provider training and patient support.
-
Harnessing male peer networks to boost HIV testing and PrEP use
A large clinical trial in South Africa tests whether giving HIV self-test kits through male peer networks, with phone support, increases PrEP uptake among men.
-
Harnessing men's peer networks to boost HIV self-testing and PrEP use
A large project in South Africa tests whether giving HIV self-test kits through men’s social networks, with phone support, can lead to more men starting PrEP and using HIV testing.
-
Microglia Help Finish Seizures and Heal the Brain
Scientists are studying how brain immune cells (microglia) help end severe seizures and repair brain damage, with potential new ideas for people who have had status epilepticus.
-
Participatory system dynamics to improve PrEP access in the Bronx
A community-driven project in the Bronx will use system dynamics to identify practical ways to help people at risk for HIV start and stay on PrEP.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.