Improving the reliability of research using mouse models
Official title: Resource Section
Funded at Baylor College of Medicine · NIH-10917294 · Data updated 2026-11-12
This study is working to make sure that research using mice for medical studies is more reliable and clear, which can help scientists create safer and better treatments for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | December 1, 2023 |
| Project end | November 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $186,669 |
| NIH project number | 5U42OD035581-02 |
| Project ID | NIH-10917294 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include patients involved in clinical trials that rely on preclinical data from mouse models.
✕Less likely to help
Patients who are not involved in clinical trials or whose conditions are not studied using mouse models may not receive direct benefits from this research.
What this research studies
This research focuses on enhancing the reproducibility and transparency of studies that use mouse models for preclinical research. It aims to establish standardized maintenance protocols for these models to ensure their genetic stability and integrity. By centralizing resources and expertise, the project seeks to improve the quality of data generated from these studies, which is crucial for assessing new medical technologies, including genome editing. Patients may benefit indirectly through more reliable research outcomes that lead to safer and more effective treatments.
Why it matters
Potential benefit: If successful, this research could lead to more reliable preclinical studies, ultimately resulting in safer and more effective medical treatments for patients.
How similar studies have gone: Previous initiatives, such as the Knockout Mouse Phenotyping Project, have shown success in improving the reliability of research using standardized mouse models.
Where this research is happening
-
Baylor College of Medicine
Houston, United States Active
Researchers
- Principal investigator: Lanza, Denise Grant — Baylor College of Medicine
- Study coordinator: Lanza, Denise Grant
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.