Improving survival rates after cardiac arrest using new techniques

Head Up CPR and Aortic Occlusion to Improve Survival after Refractory Cardiac Arrest

NIH-funded research Advancedcpr Solutions LLC · NIH-11067147

This study is looking at new ways to help people who have a cardiac arrest and don’t respond to regular CPR, using a special technique that keeps blood flowing to important organs, to see if it can improve their chances of survival.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionAdvancedcpr Solutions LLC NIH-funded
Lab location1 site (Minneapolis, United States)
Project IDNIH-11067147 on NIH RePORTER

What this research studies

This research investigates innovative methods to enhance survival rates for patients experiencing refractory cardiac arrest, a condition where standard resuscitation techniques fail. The approach involves the use of head-up CPR combined with aortic occlusion to improve blood flow and oxygen delivery to vital organs during cardiac arrest. By focusing on patients who do not respond to conventional CPR and defibrillation, the study aims to develop a more effective treatment strategy. Patients will be monitored closely to assess the effectiveness of these new techniques in real-time.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults experiencing refractory cardiac arrest who have not responded to standard resuscitation efforts.

Not a fit: Patients who are not experiencing cardiac arrest or those who have already received successful resuscitation will not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly increase survival rates and improve outcomes for patients suffering from refractory cardiac arrest.

How similar studies have performed: While there have been limited successes with similar approaches, this research aims to explore a novel combination of techniques that have not been widely tested together.

Where this research is happening

Minneapolis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.