Improving stored red blood cells for trauma care
Official title: Improving red blood cell storage for trauma resusciation
Funded at University of Cincinnati · NIH-11403782 · Data updated 2026-11-12
Aimed at making stored red blood cells safer for people who have severe bleeding from trauma.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Cincinnati NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project start | September 1, 2025 |
| Project end | August 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $405,000 |
| NIH project number | 5R35GM158428-02 |
| Project ID | NIH-11403782 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with severe trauma who require transfusions and are at risk of hemorrhage.
✕Less likely to help
Patients not needing transfusion or those with conditions unrelated to stored blood risks may not benefit.
What this research studies
This project looks at why stored red blood cells (pRBCs) may harm trauma patients and seeks ways to store them better to reduce complications after transfusion. By studying the biochemical changes that happen during storage and how these cells affect the lungs and other organs, the team plans targeted approaches to lessen inflammation and tissue damage. The work builds on prior findings about microparticles in stored blood and aims to translate those insights into improved storage practices and better patient outcomes.
Why it matters
Potential benefit: If successful, the research could lead to safer transfusions and fewer organ complications after trauma.
How similar studies have gone: Previous work suggests that modifying stored blood components can reduce inflammatory responses and organ injury, indicating potential benefit from this approach.
Where this research is happening
-
University of Cincinnati
Cincinnati, United States Active
Researchers
- Principal investigator: Pritts, Timothy a — University of Cincinnati
- Study coordinator: Pritts, Timothy a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.