Improving radiation therapy for brain tumors using advanced imaging techniques

Improving Image-Guided Radiation Therapy of Gliomas with High-Resolution MR Spectroscopic Imaging

NIH-funded research Yale University · NIH-10897779

This study is looking at how a special type of brain scan can help doctors better plan radiation treatment for patients with gliomas, which are brain tumors, so they can target the tumors more accurately and improve treatment results.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University NIH-funded
Lab location1 site (New Haven, United States)
Project IDNIH-10897779 on NIH RePORTER

What this research studies

This research focuses on enhancing the treatment of gliomas, a type of brain tumor, by using high-resolution MR spectroscopic imaging (MRSI) to improve the accuracy of radiation therapy planning. Currently, the standard imaging methods may not precisely define tumor boundaries, which can lead to less effective treatment. By integrating MRSI, the research aims to provide a more detailed view of the tumor's characteristics, potentially allowing for more targeted and effective radiation doses. This approach could lead to better outcomes for patients undergoing treatment for gliomas.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients diagnosed with gliomas who are undergoing treatment involving radiation therapy.

Not a fit: Patients with non-glioma brain tumors or those not receiving radiation therapy may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective radiation therapy for glioma patients, improving their treatment outcomes and quality of life.

How similar studies have performed: Previous studies using MR spectroscopic imaging in glioblastoma patients have shown promising results, indicating potential for success in this research approach.

Where this research is happening

New Haven, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.