Improving PrEP outcomes for pregnant women in Botswana with integrated STI testing and PrEP delivery

Who could benefit from this research

What this research studies

This project focuses on pregnant and postpartum women at risk of HIV in Botswana. It plans to test an integrated antenatal care approach that includes STI testing and different PrEP options to improve uptake and adherence. The team will compare oral PrEP and the dapivirine vaginal ring, looking at safety and how well women stick with the method they choose. By refining risk messaging and addressing pill burden and safety concerns, the study seeks to make PrEP more acceptable during pregnancy and breastfeeding.

Why it matters

Where this research is happening

• The Botswana Harvard Health Partnership
  Gaborone, Botswana Active

Researchers

• Principal investigator: Morroni, Chelsea — The Botswana Harvard Health Partnership
• Study coordinator: Morroni, Chelsea

Related research

Other NIH-funded projects on the same topics.

• Safer PrEP dosing for pregnant women in sub‑Saharan Africa

  Seeing if higher daily doses of the HIV prevention pill FTC/TDF during pregnancy help women in sub‑Saharan Africa maintain stronger protection from HIV.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11512886

• Better HIV prevention pills for pregnant women in sub‑Saharan Africa

  Compares standard and higher daily PrEP pill doses to find the safest, most protective option for pregnant women in sub‑Saharan Africa.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11322082

• HIV prevention for pregnant and postpartum women in Botswana using STI testing and PrEP options

  This project offers STI testing plus two HIV prevention choices—daily oral PrEP pills and a dapivirine vaginal ring—to help pregnant and postpartum women in Botswana avoid HIV.

  NIH research The Botswana Harvard Health Partnership · Gaborone, Botswana · NIH-11181264

• Finding the best PrEP doses for pregnant women in sub-Saharan Africa

  This study is looking at the best way to give HIV prevention medication to pregnant women in sub-Saharan Africa to help keep them safe from HIV, and it will involve trying different doses during their pregnancy and checking how well it works and how safe it is afterward.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11077771

• Improving HIV prevention for pregnant women in Botswana

  This study is looking at ways to help pregnant women in Botswana use HIV prevention methods more easily, by combining STI testing with PrEP services during their check-ups, so they can stay healthy and protect their babies.

  NIH research Botswana-Harvard AIDS Institute · Gaborone, Botswana · NIH-10991057

• mChoice: Boosting PrEP Use and Adherence for Black and Latino MSM with Tailored Training and Support

  A national study to help Black and Latino men who have sex with men start and stick with PrEP through culturally matched provider training and patient support.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11624204

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.