Improving HIV prevention for pregnant women in Botswana
Improving PrEP outcomes among pregnant women in Botswana with an integrated STI testing and PrEP delivery model
['FUNDING_R01'] · BOTSWANA-HARVARD AIDS INSTITUTE · NIH-10991057
This study is looking at ways to help pregnant women in Botswana use HIV prevention methods more easily, by combining STI testing with PrEP services during their check-ups, so they can stay healthy and protect their babies.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOTSWANA-HARVARD AIDS INSTITUTE (nih funded) |
| Locations | 1 site (GABORONE, BOTSWANA) |
| Trial ID | NIH-10991057 on ClinicalTrials.gov |
What this research studies
This research focuses on enhancing the use of HIV pre-exposure prophylaxis (PrEP) among pregnant women in Botswana, where the risk of HIV acquisition is significantly higher during pregnancy and postpartum. The project aims to integrate STI testing with PrEP delivery in antenatal care settings to improve access and adherence to PrEP. By addressing barriers such as low perceived risk and side effects, the study seeks to refine the safety profile of PrEP options like the dapivirine vaginal ring. The approach includes evaluating the effectiveness of these strategies to ensure better health outcomes for mothers and infants.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women in Botswana who are at risk of HIV infection.
Not a fit: Patients who are not pregnant or who do not have a risk of HIV infection may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce HIV transmission rates among pregnant women, leading to healthier outcomes for both mothers and their babies.
How similar studies have performed: Previous research has shown promising results in integrating PrEP delivery with antenatal care, indicating that this approach could be effective.
Where this research is happening
GABORONE, BOTSWANA
- BOTSWANA-HARVARD AIDS INSTITUTE — GABORONE, BOTSWANA (ACTIVE)
Researchers
- Principal investigator: MORRONI, CHELSEA — BOTSWANA-HARVARD AIDS INSTITUTE
- Study coordinator: MORRONI, CHELSEA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus