Improving HIV prevention for pregnant women in Botswana

Who could benefit from this research

What this research studies

This research focuses on enhancing the use of HIV pre-exposure prophylaxis (PrEP) among pregnant women in Botswana, where the risk of HIV acquisition is significantly higher during pregnancy and postpartum. The project aims to integrate STI testing with PrEP delivery in antenatal care settings to improve access and adherence to PrEP. By addressing barriers such as low perceived risk and side effects, the study seeks to refine the safety profile of PrEP options like the dapivirine vaginal ring. The approach includes evaluating the effectiveness of these strategies to ensure better health outcomes for mothers and infants.

Why it matters

Where this research is happening

• Botswana-Harvard AIDS Institute
  Gaborone, Botswana Active

Researchers

• Principal investigator: Morroni, Chelsea — Botswana-Harvard AIDS Institute
• Study coordinator: Morroni, Chelsea

Related research

Other NIH-funded projects on the same topics.

• Safer PrEP dosing for pregnant women in sub‑Saharan Africa

  Seeing if higher daily doses of the HIV prevention pill FTC/TDF during pregnancy help women in sub‑Saharan Africa maintain stronger protection from HIV.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11512886

• Improving PrEP outcomes for pregnant women in Botswana with integrated STI testing and PrEP delivery

  A study in Botswana aims to help pregnant and postpartum women use HIV prevention methods more effectively by mixing STI testing with choices like oral PrEP and the dapivirine vaginal ring.

  NIH research The Botswana Harvard Health Partnership · Gaborone, Botswana · NIH-11388608

• Better HIV prevention pills for pregnant women in sub‑Saharan Africa

  Compares standard and higher daily PrEP pill doses to find the safest, most protective option for pregnant women in sub‑Saharan Africa.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11322082

• HIV prevention for pregnant and postpartum women in Botswana using STI testing and PrEP options

  This project offers STI testing plus two HIV prevention choices—daily oral PrEP pills and a dapivirine vaginal ring—to help pregnant and postpartum women in Botswana avoid HIV.

  NIH research The Botswana Harvard Health Partnership · Gaborone, Botswana · NIH-11181264

• Finding the best PrEP doses for pregnant women in sub-Saharan Africa

  This study is looking at the best way to give HIV prevention medication to pregnant women in sub-Saharan Africa to help keep them safe from HIV, and it will involve trying different doses during their pregnancy and checking how well it works and how safe it is afterward.

  NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11077771

• mChoice: Boosting PrEP Use and Adherence for Black and Latino MSM with Tailored Training and Support

  A national study to help Black and Latino men who have sex with men start and stick with PrEP through culturally matched provider training and patient support.

  NIH research Columbia University Health Sciences · New York, United States · NIH-11624204

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.