NIH-funded research U01 cooperative agreement

Improving newborn health with rapid malaria testing in pregnancy in Africa

Official title: Improving Neonatal health Through Rapid malaria testing in Early Pregnancy with high-sensitivity Diagnostics (INTREPiD)

Funded at Duke University · NIH-11520770 · Data updated 2026-11-12

A funded project will test high-sensitivity malaria rapid tests to help manage malaria in pregnant people in Africa, aiming to reduce infant deaths and improve newborn health.

More Pregnancy research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionDuke University
NIH-funded
Lab location1 site (Durham, United States)
Project startApril 1, 2022
Project endMarch 31, 2027
Funding year2026
Award (this year)$233,902
NIH project number3U01AI162463-05S2
Project IDNIH-11520770 on NIH RePORTER

Who could benefit from this research

Could help

Pregnant people in the first, second, or third trimester in Kenya or DR Congo who are at risk for malaria.

Less likely to help

Pregnant people in settings without malaria risk or without access to early antenatal care may not benefit.

What this research studies

This project partners with Kenya and DR Congo to bring rapid malaria testing into early pregnancy care. It uses high-sensitivity tests to detect low-density infections and plans to integrate first-trimester screening into routine antenatal care. The study aligns with global health goals to reduce maternal and neonatal mortality and to accelerate adoption of new health tools in resource-limited settings.

Why it matters

Potential benefit: If successful, the approach could lower newborn deaths related to malaria by enabling earlier, targeted treatment.

How similar studies have gone: Previous rapid tests have reduced malaria burden in pregnancy, but this project focuses on first-trimester screening and high-sensitivity detection in Africa.

Where this research is happening

  • Duke University
    Durham, United States
    Active

Researchers

  • Principal investigator: Taylor, Steve Myer — Duke University
  • Study coordinator: Taylor, Steve Myer

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.