Improving imaging techniques to predict pulmonary fibrosis progression

Advanced Imaging for Pulmonary Fibrosis

NIH-funded research Massachusetts General Hospital · NIH-10979870

This study is looking at new imaging techniques to help spot patients who might develop worsening lung scarring from certain lung diseases before they show serious symptoms, so they can start treatment sooner and manage their care better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10979870 on NIH RePORTER

What this research studies

This research focuses on enhancing imaging methods to accurately identify patients at risk of developing progressive pulmonary fibrosis (PPF) from non-idiopathic pulmonary fibrosis interstitial lung disease (ILD). By utilizing advanced imaging technologies, including a novel PET probe, the study aims to predict disease progression before significant symptoms arise. This early identification could lead to timely antifibrotic therapy and better management of patient care plans. The goal is to improve outcomes for patients with non-IPF ILD by enabling early intervention and tailored treatment strategies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with non-IPF interstitial lung disease who are at risk of developing progressive pulmonary fibrosis.

Not a fit: Patients with idiopathic pulmonary fibrosis or those who do not have interstitial lung disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to earlier diagnosis and treatment for patients at risk of progressive pulmonary fibrosis, potentially improving survival rates.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for similar conditions, indicating potential for success in this novel approach.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancers
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.