Improving imaging techniques to predict pulmonary fibrosis progression
Official title: Advanced Imaging for Pulmonary Fibrosis
Funded at Massachusetts General Hospital · NIH-10979870 · Data updated 2026-11-12
This study is looking at new imaging techniques to help spot patients who might develop worsening lung scarring from certain lung diseases before they show serious symptoms, so they can start treatment sooner and manage their care better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 1, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $604,115 |
| NIH project number | 1R01HL171240-01A1 |
| Project ID | NIH-10979870 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with non-IPF interstitial lung disease who are at risk of developing progressive pulmonary fibrosis.
✕Less likely to help
Patients with idiopathic pulmonary fibrosis or those who do not have interstitial lung disease may not benefit from this research.
What this research studies
This research focuses on enhancing imaging methods to accurately identify patients at risk of developing progressive pulmonary fibrosis (PPF) from non-idiopathic pulmonary fibrosis interstitial lung disease (ILD). By utilizing advanced imaging technologies, including a novel PET probe, the study aims to predict disease progression before significant symptoms arise. This early identification could lead to timely antifibrotic therapy and better management of patient care plans. The goal is to improve outcomes for patients with non-IPF ILD by enabling early intervention and tailored treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and treatment for patients at risk of progressive pulmonary fibrosis, potentially improving survival rates.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for similar conditions, indicating potential for success in this novel approach.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Montesi, Sydney — Massachusetts General Hospital
- Study coordinator: Montesi, Sydney
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.