Improving imaging techniques for sarcoma surgeries

Fluorescence lifetime-based intraoperative imaging system for sarcoma surgeries

NIH-funded research Massachusetts Eye and Ear Infirmary · NIH-11101953

This study is testing a new imaging system that helps surgeons see tumors better during sarcoma surgeries, making it easier to remove cancer while protecting healthy tissue, which could lead to fewer recurrences and better recovery for patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts Eye and Ear Infirmary NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11101953 on NIH RePORTER

What this research studies

This research focuses on developing a new imaging system that uses fluorescence lifetime to enhance the visualization of tumors during sarcoma surgeries. By providing real-time feedback to surgeons, this technique aims to improve the accuracy of tumor removal while minimizing damage to surrounding healthy tissue. The study evaluates the use of specific contrast agents to differentiate between cancerous and normal tissues, addressing the limitations of current imaging methods that rely on subjective assessments. The goal is to reduce the rates of cancer recurrence and improve patient outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients diagnosed with sarcomas who are scheduled for surgical resection.

Not a fit: Patients with sarcomas that are not operable or those who are not candidates for surgery may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more precise surgical procedures for sarcoma patients, reducing the likelihood of cancer recurrence and improving overall quality of life.

How similar studies have performed: Previous research has shown promising results with fluorescence imaging techniques in other types of cancer surgeries, indicating potential for success in this novel application.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.