Improving how liquid biopsy samples are processed and stored for cancer testing.
Guidelines for processing and storing liquid biopsy samples for functional assays in research and clinical testing.
This study is looking at the best ways to collect and store blood and bone marrow samples from leukemia patients to make sure tests for cancer treatment are as accurate as possible, helping doctors provide better care for people with acute myeloid leukemia and other cancers.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project ID | NIH-10862478 on NIH RePORTER |
What this research studies
This research focuses on establishing standardized guidelines for processing and storing liquid biopsy samples, such as blood and bone marrow, which are essential for functional assays in cancer diagnosis and treatment. By analyzing samples from over 2,500 leukemia patients, the project aims to identify how different pre-analytical factors affect the reliability of test results. The goal is to enhance the accuracy of precision medicine approaches in treating acute myeloid leukemia (AML) and other cancers. This work will involve collaboration across various institutions to ensure consistent practices in sample handling.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with acute myeloid leukemia (AML) or other related blood cancers.
Not a fit: Patients with solid tumors or those not undergoing liquid biopsy testing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and reliable cancer diagnostics, ultimately improving treatment outcomes for patients.
How similar studies have performed: Previous research has shown that standardizing sample processing can significantly improve the reliability of diagnostic tests, indicating a promising approach in this area.
Where this research is happening
Portland, United States
- Oregon Health & Science University — Portland, United States (Active)
Researchers
- Principal investigator: Vu, Tothu Q — Oregon Health & Science University
- Study coordinator: Vu, Tothu Q
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.