Improving heart rhythm treatment using advanced imaging techniques
Official title: Peri-procedural transmural electrophysiological imaging of scar-related ventricular tachycardia
Funded at Rochester Institute of Technology · NIH-10558577 · Data updated 2026-11-12
This study is looking to improve how we treat ventricular tachycardia, a serious heart issue, by creating a new imaging method that combines heart electrical activity with MRI scans, helping doctors find and treat the problem areas more effectively.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rochester Institute of Technology NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | February 8, 2019 |
| Project end | January 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $505,846 |
| NIH project number | 5R01HL145590-05 |
| Project ID | NIH-10558577 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with ventricular tachycardia related to myocardial scarring.
✕Less likely to help
Patients without a history of ventricular tachycardia or those whose arrhythmias are not related to myocardial scars may not benefit from this research.
What this research studies
This research focuses on enhancing the treatment of ventricular tachycardia (VT), a serious heart condition caused by abnormal electrical circuits in scarred heart tissue. The project aims to develop a new imaging technique that combines electrical activity data with MRI scans to better identify and target these problematic areas before and after treatment. By utilizing electrocardiographic imaging, the researchers hope to provide more accurate information about the heart's electrical activity, which could lead to more effective ablation procedures. This approach seeks to overcome the limitations of current mapping techniques that often miss critical data during treatment.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with ventricular tachycardia, potentially reducing the risk of life-threatening heart events.
How similar studies have gone: Other research has shown promise in using advanced imaging techniques for cardiac arrhythmias, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
-
Rochester Institute of Technology
Rochester, United States Active
Researchers
- Principal investigator: Wang, Linwei — Rochester Institute of Technology
- Study coordinator: Wang, Linwei
Related research
Other NIH-funded projects on the same topics.
-
Map heart tissue to guide VT ablation with AI help
A patient-oriented project aims to use AI-based mapping to better identify abnormal heart tissue responsible for ventricular tachycardia and guide safer, faster ablation.
-
Proton SBRT for refractory ventricular tachycardia with real-time 3D/4D imaging
A patient-facing study exploring a proton-based, noninvasive radiation therapy to treat stubborn VT using advanced 3D and 4D imaging to target the heart safely.
-
Venous ethanol ablation to treat ischemic VT (VE-VT)
A new treatment approach uses ethanol delivered through heart veins to help stop dangerous heart rhythms in patients with previous heart damage.
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Novel gene therapy tools to prevent dangerous heart rhythms
A small grant supports testing gene-therapy methods to stop ventricular tachycardia after a heart attack, with the goal of helping people at risk of sudden heart rhythm problems.
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Radiation-guided ablation for ventricular tachycardia
This project tests a noninvasive radiation approach to ablate heart tissue in people with dangerous ventricular tachycardia to reduce the need for invasive procedures.
-
Low-Field MRI–Guided Robotic Catheter System for VT Ablation
A research project is testing a new low-field MRI–guided robotic catheter to improve treatment of ventricular tachycardia for patients with abnormal heart structure.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.