Improving heart disease diagnosis using advanced imaging techniques

Novel methodologies to improve coronary artery disease diagnostics with dynamic PET

NIH-funded research University of Cincinnati · NIH-10982092

This study is looking at new ways to take clearer pictures of blood flow in the heart to help doctors better diagnose coronary artery disease, so patients can get more accurate diagnoses and personalized treatment plans.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Cincinnati NIH-funded
Lab location1 site (Cincinnati, United States)
Project IDNIH-10982092 on NIH RePORTER

What this research studies

This research focuses on enhancing the diagnosis of coronary artery disease (CAD) through innovative imaging methods known as dynamic PET myocardial perfusion imaging. By utilizing advanced algorithms and deep learning techniques, the project aims to improve the accuracy of blood flow measurements in the heart, which can lead to better assessments of CAD. The approach involves developing new methods to reduce noise in imaging data, allowing for clearer and more precise images that can aid in diagnosis. Patients may benefit from more accurate diagnoses and tailored treatment plans based on improved imaging results.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing symptoms of coronary artery disease or those at high risk for developing heart conditions.

Not a fit: Patients with non-cardiac related health issues or those who do not exhibit symptoms of coronary artery disease may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses of coronary artery disease, potentially improving patient outcomes and treatment strategies.

How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for diagnosing heart conditions, suggesting that this approach could yield significant advancements.

Where this research is happening

Cincinnati, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.