Improving early detection of keratoconus using advanced imaging technology
Wide-field corneal microlayer tomography for keratoconus
This study is testing a new imaging technology that helps doctors spot keratoconus earlier by taking detailed pictures of the eye's surface, which could lead to better treatment and help protect your vision.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-11004118 on NIH RePORTER |
What this research studies
This research focuses on developing a new imaging technology called Widefield Corneal Microlayer Tomography (wCMT) to detect keratoconus at earlier stages. By using high-resolution optical coherence tomography (OCT), the study aims to visualize and quantify changes in the corneal microstructure, specifically in the epithelium and Bowman’s layer. This could lead to better diagnosis and management of keratoconus, potentially preventing vision loss through earlier intervention. The project will involve testing this technology on individuals diagnosed with keratoconus to validate its effectiveness.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with keratoconus or those at risk of developing the condition.
Not a fit: Patients with advanced keratoconus or those who have already undergone corneal transplantation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier diagnosis and treatment of keratoconus, significantly reducing the risk of vision loss for patients.
How similar studies have performed: Previous research has shown promise in using advanced imaging techniques for early detection of corneal diseases, suggesting that this approach may also be effective for keratoconus.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Ruggeri, Marco — University of Miami School of Medicine
- Study coordinator: Ruggeri, Marco
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.