NIH-funded research R21 grant

Improving cancer detection using advanced light technology and machine learning

Official title: Metasurface enhanced and machine learning aided spectrochemical liquid biopsy

Funded at University of Wisconsin-Madison · NIH-11030790 · Data updated 2026-11-12

This study is working on a new, easy way to find cancer markers in body fluids without needing invasive procedures, using advanced technology to make early detection and monitoring of cancer more accurate and convenient for patients.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Wisconsin-Madison
NIH-funded
Lab location1 site (Madison, United States)
Project startMarch 1, 2023
Project endFebruary 28, 2026
Funding year2025
Award (this year)$148,840
NIH project number5R21EB034411-03
Project IDNIH-11030790 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals at risk for cancer or those undergoing monitoring for cancer recurrence.

Less likely to help

Patients with cancers that are not detectable through liquid biopsy methods may not benefit from this research.

What this research studies

This research focuses on developing a new method for detecting cancer-related biomarkers in body fluids through a non-invasive liquid biopsy approach. By utilizing advanced spectrochemical techniques, such as Raman and infrared spectroscopy, combined with machine learning, the project aims to enhance the sensitivity and accuracy of cancer detection. The innovative use of electromagnetic metasurfaces is expected to improve the performance of these diagnostic tools, making them more effective for early cancer detection and patient monitoring. Ultimately, the goal is to create a portable and user-friendly platform that can be used in clinical settings.

Why it matters

Potential benefit: If successful, this research could lead to earlier and more accurate cancer detection, potentially improving survival rates for patients.

How similar studies have gone: Other research has shown promise in using advanced spectrochemical techniques for cancer detection, indicating that this approach could be a significant advancement in the field.

Where this research is happening

  • University of Wisconsin-Madison
    Madison, United States
    Active

Researchers

  • Principal investigator: Yesilkoy, Filiz — University of Wisconsin-Madison
  • Study coordinator: Yesilkoy, Filiz

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.