Improving brain imaging quality and consistency

Resolution Enhancement and Contrast Harmonization for MR Neuroimaging

NIH-funded research Johns Hopkins University · NIH-11130411

This study is working on improving MRI scans of the brain to make them clearer and more consistent, so doctors can better diagnose and manage neurological conditions, ultimately helping patients get more accurate care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11130411 on NIH RePORTER

What this research studies

This research focuses on enhancing the quality and consistency of magnetic resonance (MR) neuroimaging, which is crucial for diagnosing and managing neurological diseases. It aims to address the variability in MR images caused by differences in hardware and software across imaging centers. By developing advanced algorithms for image processing, the project seeks to standardize the appearance of MR images, making them more reliable for clinical assessments and research. Patients may benefit from more accurate diagnoses and better monitoring of their neurological conditions as a result of this improved imaging technology.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals undergoing MR neuroimaging for neurological conditions such as multiple sclerosis, Alzheimer's disease, or other brain disorders.

Not a fit: Patients who do not require MR neuroimaging or those with conditions that do not involve neurological assessment may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and treatment plans for patients with neurological diseases.

How similar studies have performed: Previous research has shown success in improving imaging techniques, indicating that this approach has the potential for meaningful advancements in neuroimaging.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.