Improved, safer vertebral fracture treatment for older adults using a minimally invasive regenerative adhesive
Official title: Improved Treatment Options for Vertebral Compression Fractures in Elderly Patients Using Minimally Invasive, Image-Guided Delivery of a Regenerative Bone Adhesive
Funded at Revbio, INC. · NIH-11420547 · Data updated 2026-11-12
A new, gentler treatment option for vertebral compression fractures in seniors using image-guided delivery of a regenerative bone adhesive.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Revbio, INC. NIH-funded |
| Lab location | 1 site (Lowell, UNITED STATES) |
| Project start | September 30, 2025 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $205,450 |
| NIH project number | 5R44AG097243-02 |
| Project ID | NIH-11420547 on NIH RePORTER |
Who could benefit from this research
✓Could help
Older adults with vertebral compression fractures who are candidates for minimally invasive spine procedures.
✕Less likely to help
Some patients may not benefit if their fractures are not amenable to adhesive-based healing or have contraindications to the procedure.
What this research studies
This project aims to offer an alternative to traditional cement injections for elderly patients with painful spine fractures. It will test a minimally invasive method guided by imaging to place a regenerative bone adhesive into the fractured vertebrae. The approach focuses on reducing complications like cement leakage while improving pain relief and quality of life. The study involves translational work that could move toward clinical use for older adults suffering from osteoporosis-related fractures.
Why it matters
Potential benefit: If successful, patients could experience safer procedures with less pain and faster recovery.
How similar studies have gone: Prior spine augmentation approaches improved pain but carried notable complication risks; this project explores a potentially safer adhesive-based option.
Where this research is happening
-
Revbio, INC.
Lowell, United States Active
Researchers
- Principal investigator: Mcdonough, Brittany — Revbio, INC.
- Study coordinator: Mcdonough, Brittany
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.