Improve brain tumor radiation planning with high-resolution MR spectroscopy

Who could benefit from this research

What this research studies

This project at Yale University explores how high-resolution MR spectroscopic imaging can improve delineation of glioma boundaries to guide radiation therapy. By combining metabolic information from MRSI with standard MRI, clinicians may better define tumor edges and reduce damage to healthy brain tissue. The study builds on prior phase I results showing promise for dose-escalation strategies guided by metabolic imaging. Researchers will develop imaging protocols, correlate imaging findings with pathological data, and evaluate how these insights could refine treatment planning. The goal is to translate improved imaging accuracy into more effective and safer radiation treatment for glioma patients.

Why it matters

Where this research is happening

• Yale University
  New Haven, United States Active

Researchers

• Principal investigator: Ma, Chao — Yale University
• Study coordinator: Ma, Chao

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.