How statins affect blood pressure and artery function
Official title: Arterial contractility and blood pressure regulation by statins
Funded at Mercer University Macon · NIH-11042363 · Data updated 2026-11-12
This study is looking at how statin medications, which are often used to help with heart disease, affect blood pressure and blood vessel health, so we can better understand why some people see improvements while others don’t, ultimately helping doctors tailor treatments for those with high blood pressure.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mercer University Macon NIH-funded |
| Lab location | 1 site (Macon, United States) |
| Project start | December 20, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $657,602 |
| NIH project number | 1R01HL167926-01A1 |
| Project ID | NIH-11042363 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with hypertension or those at risk for cardiovascular diseases who are currently taking or considering statin therapy.
✕Less likely to help
Patients who do not have hypertension or cardiovascular risk factors may not benefit from this research.
What this research studies
This research investigates the effects of statins, commonly prescribed medications for heart disease, on blood pressure regulation and arterial function. It aims to understand why some patients experience lower blood pressure while others do not when taking these medications. By examining the direct effects of statins on blood vessels in both normal and hypertensive animal models, the study seeks to uncover the mechanisms behind these varying responses. This knowledge could help doctors personalize treatment plans for patients with hypertension and related conditions.
Why it matters
Potential benefit: If successful, this research could lead to more effective and tailored treatments for patients with high blood pressure and cardiovascular diseases.
How similar studies have gone: Previous research has shown varying effects of statins on blood pressure, indicating that this area of investigation is both relevant and necessary for understanding their full impact.
Where this research is happening
-
Mercer University Macon
Macon, United States Active
Researchers
- Principal investigator: Hasan, Raquibul — Mercer University Macon
- Study coordinator: Hasan, Raquibul
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.