NIH-funded research R01 grant

How sleep problems affect opioid use in teens after surgery

Official title: Sleep deficiency and opioid use/misuse in adolescents following surgery

Funded at Stanford University · NIH-10925382 · Data updated 2026-11-12

This study is looking at how not getting enough sleep after surgery might lead teens to misuse their prescribed pain medications, and it hopes to find ways to help prevent this from happening.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionStanford University
NIH-funded
Lab location1 site (Stanford, United States)
Project startSeptember 10, 2023
Project endAugust 31, 2028
Funding year2024
Award (this year)$593,375
NIH project number5R01HL166337-02
Project IDNIH-10925382 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescents who are undergoing surgery and may be prescribed opioids for pain management.

Less likely to help

Patients who are not undergoing surgery or who do not have issues with sleep deficiency may not benefit from this research.

What this research studies

This research investigates the relationship between sleep deficiency and opioid misuse among adolescents following surgical procedures. It aims to identify the critical period after surgery when teens are at risk for misusing prescribed opioids and to explore the behavioral mechanisms that contribute to this risk. By examining factors such as sleep quality and psychological influences, the study seeks to provide insights that could help in developing targeted interventions to reduce opioid misuse in this vulnerable population.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing opioid misuse in adolescents after surgery.

How similar studies have gone: Other research has indicated a connection between sleep quality and substance misuse, suggesting that this approach may yield valuable insights.

Where this research is happening

  • Stanford University
    Stanford, United States
    Active

Researchers

  • Principal investigator: Groenewald, Cornelius Botha — Stanford University
  • Study coordinator: Groenewald, Cornelius Botha

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.