How IVF benefit designs shape pregnancy outcomes
Official title: How Health Insurance Benefit Design Affects Infertility Treatment and Birth Outcomes
Funded at University of Michigan at Ann Arbor · NIH-11345946 · Data updated 2026-11-12
This research looks at how employer-provided IVF insurance benefits affect the choices patients make and the health outcomes of mothers and babies.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | September 21, 2024 |
| Project end | May 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $675,712 |
| NIH project number | 5R01HD113625-03 |
| Project ID | NIH-11345946 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults over 21 undergoing or considering IVF who are affected by insurance benefit design.
✕Less likely to help
Individuals not planning or seeking IVF or those outside the covered population may not benefit.
What this research studies
Infertility affects many people, and IVF is a key option. The study will look at how different IVF benefit designs influence decisions about how many embryos to transfer and the resulting birth outcomes. Researchers will use data from patients, insurers, and providers to understand the effects of cost-sharing and coverage on health and safety. The goal is to generate evidence that can guide better insurance designs to support healthy pregnancies.
Why it matters
Potential benefit: If successful, the work could lead to insurance designs that reduce risky multiple births and improve birth outcomes for people undergoing IVF.
How similar studies have gone: Previous work showed that benefit design varies widely and can influence IVF decisions, but robust evidence on health outcomes is still needed.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Dupree, James M — University of Michigan at Ann Arbor
- Study coordinator: Dupree, James M
Related research
Other NIH-funded projects on the same topics.
-
Molecular clues to endometriosis-related infertility
This grant explores how molecular changes in endometriosis contribute to infertility, with the aim of finding better ways to diagnose and treat the condition.
-
Oral FSH receptor activator drugs to lower infertility treatment costs
A new oral drug approach aims to improve fertility treatments by using a small molecule that activates the FSH receptor, potentially making infertility care more affordable.
-
Prediction of ART outcomes for male factor infertility using single-molecule chromatin stenciling in sperm
A new test called sperm Fiber-seq is being developed to better predict how well ART will work for couples dealing with male-factor infertility.
-
TLR4 blocker for improving fertility in PCOS
A promising, already-approved drug (disulfiram) will be tested to see if it can reduce inflammation and improve ovulation in women with PCOS.
-
Innovative 3D-printed vaginal ring for progesterone delivery to support IVF pregnancies
A new 3D-printed vaginal ring delivers progesterone over 28 days for IVF patients, aiming to improve pregnancy success with fewer rings and less frequent dosing.
-
Genetics of Male Infertility: Accelerating Discovery and Clinical Impact
This grant aims to uncover the genetic causes of male infertility (azoospermia) to improve diagnosis and pave the way for personalized treatments.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.