How endurance training affects fat cell development and function
Official title: Adipogenesis, triglyceride turnover and cellular composition of adipose tissue in response to endurance training (ATLAS)
Funded at Adventhealth Orlando · NIH-11064026 · Data updated 2026-11-12
This study is looking at how doing endurance exercise can improve the health of your fat tissue and help with insulin resistance, so if you're interested in how exercise can boost your overall health, this research might be for you!
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Adventhealth Orlando NIH-funded |
| Lab location | 1 site (Orlando, United States) |
| Project start | April 1, 2024 |
| Project end | March 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $700,459 |
| NIH project number | 5R01DK133529-02 |
| Project ID | NIH-11064026 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults who are experiencing issues related to obesity, insulin resistance, or metabolic disorders.
✕Less likely to help
Patients who are not overweight or do not have metabolic health issues may not benefit from this research.
What this research studies
This research investigates how endurance exercise influences the quality and function of fat tissue in the body, particularly focusing on how it affects insulin resistance and fat cell turnover. By examining the biological changes in fat cells during and after exercise, the study aims to uncover the mechanisms that lead to improved metabolic health. Participants may undergo assessments involving metabolic labeling to track changes in their fat cells, providing insights into how exercise can enhance fat tissue quality and overall health.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving metabolic health and managing conditions like obesity and diabetes through exercise.
How similar studies have gone: Previous studies have shown promising results regarding the effects of exercise on fat cell biology, but this research aims to provide novel insights into the specific mechanisms involved.
Where this research is happening
-
Adventhealth Orlando
Orlando, United States Active
Researchers
- Principal investigator: Sparks, Lauren Marie — Adventhealth Orlando
- Study coordinator: Sparks, Lauren Marie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.