How diet quality and meal timing change blood proteins linked to heart disease in women
RISK FACTORS FOR CVD IN WOMEN
This project looks at how what and when women eat changes blood proteins that are tied to future coronary heart disease risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tulane University of Louisiana NIH-funded |
| Lab location | 1 site (New Orleans, United States) |
| Project ID | NIH-11177905 on NIH RePORTER |
What this research studies
You would be part of work that uses blood samples and long-term diet information collected from large groups like the Nurses’ Health Study, CARDIA, Jackson Heart Study, POUNDS LOST, and UK Biobank. Researchers will measure thousands of proteins in blood (proteomics) and link protein patterns to diet quality and circadian or temporal eating habits. They will follow how these proteomic patterns change over about 10 years and whether those changes predict new cases of coronary heart disease. Most analyses use existing cohort data and stored samples, so participation typically means being enrolled in one of those long-term studies or providing blood and detailed diet histories rather than receiving a new treatment.
Who could benefit from this research
Good fit: Adult women who are enrolled in long-term cohort studies or can provide blood samples and detailed diet and meal-timing information would be most relevant for this research.
Not a fit: People seeking immediate treatment for active or advanced coronary disease are unlikely to get direct clinical benefit from this observational biomarker research.
Why it matters
Potential benefit: If successful, this could lead to better diet and meal-timing guidance and blood-based markers to identify people at higher future risk of heart disease.
How similar studies have performed: Previous studies show diet influences circulating proteins and some proteomic markers relate to heart disease risk, but combining objective meal-timing measures with proteome-wide, decade-long prediction is relatively new.
Where this research is happening
New Orleans, United States
- Tulane University of Louisiana — New Orleans, United States (Active)
Researchers
- Principal investigator: Qi, Lu — Tulane University of Louisiana
- Study coordinator: Qi, Lu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.