NIH-funded research R01 grant

Home-based cardiac rehab after transcatheter valve procedures powered by a new mobile health program

Official title: Home-based cardiac rehabilitation using a novel mobile health exercise regimen following transcatheter heart valve interventions (HOME RUN HITTER)

Funded at Vanderbilt University Medical Center · NIH-11378352 · Data updated 2026-11-12

A large study tests a convenient home-based heart rehab program using a mobile health plan to help older adults recover well after transcatheter heart valve interventions.

More Cardiac Rehabilitation research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center
NIH-funded
Lab location1 site (Nashville, United States)
Project startJune 1, 2022
Project endMay 31, 2027
Funding year2026
Award (this year)$474,271
NIH project number5R01AG073633-05
Project IDNIH-11378352 on NIH RePORTER

Who could benefit from this research

Could help

Older adults who have had THVI and do not plan to participate in center-based cardiac rehab.

Less likely to help

Patients who prefer traditional care or cannot use mobile health technology may derive less benefit.

What this research studies

This project aims to extend the benefits of cardiac rehabilitation to people who have had transcatheter valve procedures by delivering a home-based program via a mobile health platform. It will enroll adults undergoing aortic or mitral THVI and compare a novel HBCR approach to standard care, with some participants also followed in a registry if they choose CBCR. The study uses activity monitoring and behavior support to boost physical activity, improve functional capacity, and enhance quality of life over time. Outcomes include clinical events, activity levels, QoL, and healthcare utilization across multiple centers. If successful, the program could make rehab more accessible and empower patients to manage their recovery at home.

Why it matters

Potential benefit: If successful, patients could recover better and sooner after THVI with a convenient home-based program.

How similar studies have gone: Previous cardiac rehab approaches show benefits; this trial tests a home-based model tailored to THVI patients.

Where this research is happening

  • Vanderbilt University Medical Center
    Nashville, United States
    Active

Researchers

  • Principal investigator: Lindman, Brian Richard — Vanderbilt University Medical Center
  • Study coordinator: Lindman, Brian Richard

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.