NIH-funded research U01 cooperative agreement

HIV Care and Outcomes in the Americas Network

Official title: Caribbean, Central, and South America network for HIV Epidemiology (CCASAnet)

Funded at Vanderbilt University Medical Center · NIH-11541272 · Data updated 2026-11-12

A network across the Americas is studying how people living with HIV are cared for, how well they stay in care, and how to prevent other health problems with data from many clinics.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center
NIH-funded
Lab location1 site (Nashville, United States)
Project startJune 15, 2006
Project endMay 31, 2027
Funding year2026
Award (this year)$86,779
NIH project number3U01AI069923-22S9
Project IDNIH-11541272 on NIH RePORTER

Who could benefit from this research

Could help

People living with HIV receiving care at CCASAnet sites in Argentina, Brazil, Chile, Haiti, Honduras, Mexico, Peru, and the United States, including subgroups like pregnant women, youth, and older adults.

Less likely to help

Individuals not engaged in HIV care or outside CCASAnet sites may not directly benefit.

What this research studies

CCASAnet connects HIV clinics across multiple countries to harmonize data and analyze real-world outcomes. The project develops biostatistics and informatics methods to understand the HIV care continuum, treatment responses, and associated health issues. It also provides mentorship and education to build research capacity at partner sites, aiming to improve care delivery and health outcomes for people with HIV in the region. The effort includes examining care retention, pregnancy-related care, treatment outcomes for TB coinfection, and non-communicable disease risks through observational studies nested in existing clinical data.

Why it matters

Potential benefit: Patients could benefit from improved understanding of how to keep people with HIV in care, optimize treatments, and address related health risks based on real-world evidence.

How similar studies have gone: Previous regional networks have generated actionable insights from observational data and informed care strategies across diverse settings.

Where this research is happening

  • Vanderbilt University Medical Center
    Nashville, United States
    Active

Researchers

  • Principal investigator: Castilho, Jessica L — Vanderbilt University Medical Center
  • Study coordinator: Castilho, Jessica L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.