NIH-funded research U01 cooperative agreement

Improving healthcare for patients with inherited cancer syndromes using a web-based platform

Official title: Improving identification and healthcare for patients with Inherited Cancer Syndromes: Evidence-based EMR implementation using a web-based computer platform

Funded at Vanderbilt University Medical Center · NIH-9848671 · Data updated 2026-11-12

This study is testing a new online tool called MeTree that helps people understand their risk for inherited cancer by combining their medical records and family health history, making it easier for patients and doctors to get the information they need for better care and support.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center
NIH-funded
Lab location1 site (Nashville, United States)
Project startSeptember 17, 2019
Project endAugust 31, 2025
Funding year2019
Award (this year)$5,339,027
NIH project number1U01CA232829-01A1
Project IDNIH-9848671 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals with a family history of cancer who may be at risk for inherited cancer syndromes.

Less likely to help

Patients without a family history of cancer or those who do not meet the criteria for hereditary cancer syndromes may not benefit from this research.

What this research studies

This research aims to enhance the identification and management of patients at risk for inherited cancer syndromes through a web-based platform that integrates electronic medical records (EMR) and family health history (FHH) data. By utilizing innovative bioinformatics and decision support tools, the project seeks to streamline the process of genetic counseling and testing, making it easier for patients and healthcare providers to access critical information. The platform, known as MeTree, will provide personalized risk assessments and educational resources to empower patients in understanding their genetic risks. The goal is to create a comprehensive clinical care system that improves awareness and facilitates timely interventions for those at risk.

Why it matters

Potential benefit: If successful, this research could lead to earlier identification and better management of hereditary cancer syndromes, ultimately improving patient outcomes.

How similar studies have gone: Previous research has shown success in using similar bioinformatics approaches to improve genetic risk assessment and patient management in hereditary cancer syndromes.

Where this research is happening

  • Vanderbilt University Medical Center
    Nashville, United States
    Active

Researchers

  • Principal investigator: Wiesner, Georgia L — Vanderbilt University Medical Center
  • Study coordinator: Wiesner, Georgia L

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.