NIH-funded research U01 cooperative agreement

HIV care and outcomes in the Americas: CCASAnet network study

Official title: Caribbean, Central, and South America network for HIV Epidemiology (CCASAnet)

Funded at Vanderbilt University Medical Center · NIH-11541267 · Data updated 2026-11-12

A research effort in the Americas is studying how people living with HIV receive care and how well treatments work across several countries.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center
NIH-funded
Lab location1 site (Nashville, United States)
Project startJune 15, 2006
Project endMay 31, 2028
Funding year2026
Award (this year)$60,653
NIH project number3U01AI069923-22S4
Project IDNIH-11541267 on NIH RePORTER

Who could benefit from this research

Could help

People living with HIV across Argentina, Brazil, Chile, Haiti, Honduras, Mexico, Peru, and the United States who are part of the CCASAnet network.

Less likely to help

Patients who are not accessing care within the participating sites or who are not represented in the CCASAnet data may not directly benefit.

What this research studies

CCASAnet is a long-running, collaborative network that gathers HIV care and research data from sites in the Americas. The project harmonizes clinical and research data to understand care gaps, outcomes, and the impact of treatments in real-world settings. It also aims to mentor new researchers and advance data methods to support observational HIV research. Over the next funding cycle, the team will look at the HIV care continuum, people lost to follow-up, pregnancies, and the influence of comorbidities like obesity, mental health, and tuberculosis on treatment outcomes. It will include prospective studies nested within existing cohorts to explore these issues.

Why it matters

Potential benefit: Improved understanding of HIV care delivery and outcomes could guide better treatment and support services for people living with HIV in the region.

How similar studies have gone: Past CCASAnet and leDEA research have produced actionable insights on HIV care and outcomes in diverse settings, with ongoing observational findings guiding care improvements.

Where this research is happening

  • Vanderbilt University Medical Center
    Nashville, United States
    Active

Researchers

  • Principal investigator: Castilho, Jessica L — Vanderbilt University Medical Center
  • Study coordinator: Castilho, Jessica L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.