NIH-funded research U01 cooperative agreement

Healthy Brain and Child Development across the first 10 years

Official title: 5/24 Healthy Brain and Child Development National Consortium

Funded at Boston Children's Hospital · NIH-11518966 · Data updated 2026-11-12

This grant supports a large study following 7,200 mothers and their babies across 27 US sites to map how early life experiences shape brain development.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionBoston Children's Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 30, 2021
Project endJune 30, 2027
Funding year2026
Award (this year)$2,275,325
NIH project number4U01DA055353-06
Project IDNIH-11518966 on NIH RePORTER

Who could benefit from this research

Could help

Families expecting a baby or with a child up to age 10, across diverse backgrounds, who participate in imaging, assessments, and biospecimen collection.

Less likely to help

Families not able to participate due to medical or logistical reasons may not directly benefit.

What this research studies

The project will use brain imaging (MRI, EEG), behavioral tests, physiological and psychological tools, and biospecimens to chart normal developmental trajectories from birth to age 10. A harmonized protocol and extensive data sharing will create a rich resource for researchers while focusing on how prenatal and early-life environments influence outcomes. Families participate through assessments and biosample collection, with data destined to support future understanding and care for neurodevelopmental health.

Why it matters

Potential benefit: If successful, this work could improve how we identify and support children at risk for neurodevelopmental issues from early life.

How similar studies have gone: Previous studies in neurodevelopment have shown that early environments influence brain development, and this project aims to harmonize data across a large cohort for broader insights.

Where this research is happening

  • Boston Children's Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Grant, Patricia Ellen — Boston Children's Hospital
  • Study coordinator: Grant, Patricia Ellen

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.