NIH-funded research U01 cooperative agreement

Healthy Brain and Child Development: a large study tracking how early life experiences shape child brain growth

Official title: 9/24- Healthy Brain and Child Development National Consortium

Funded at Northwestern University · NIH-11518965 · Data updated 2026-11-12

This project follows thousands of mothers and infants to map how genes, environments, and early experiences influence brain development over the first 10 years.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionNorthwestern University
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 30, 2021
Project endJune 30, 2027
Funding year2026
Award (this year)$1,567,968
NIH project number4U01DA055355-06
Project IDNIH-11518965 on NIH RePORTER

Who could benefit from this research

Could help

Expectant mothers and their infants, including diverse populations across the US, from pregnancy through early childhood.

Less likely to help

Families not enrolled or not meeting participation criteria for imaging, biospecimen collection, or follow-up visits may not directly benefit.

What this research studies

The Healthy Brain and Child Development Consortium will enroll about 7,200 mother-infant pairs across 27 sites to collect brain imaging, EEG, behavioral data, and biospecimens. Researchers will harmonize protocols and create a rich, shared dataset to chart typical developmental trajectories in diverse populations. The goal is to understand how prenatal and early-life exposures affect neurodevelopment and long-term outcomes, with findings shared with the scientific and medical communities to improve care for children.

Why it matters

Potential benefit: If successful, the study could inform safer environments and early interventions to support healthy brain development in children.

How similar studies have gone: Previous large, harmonized developmental studies have shown that standardized imaging and behavioral data can reveal important developmental patterns; this project builds on those foundations with a broader scope.

Where this research is happening

  • Northwestern University
    Chicago, United States
    Active

Researchers

  • Principal investigator: Wakschlag, Lauren S — Northwestern University
  • Study coordinator: Wakschlag, Lauren S

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.