Health effects of metal mixtures from abandoned uranium mines

Biomarkers and mechanisms of metal and mixed metal exposures

NIH-funded research University of New Mexico Health Scis Ctr · NIH-11124905

This work looks at how metal exposures from abandoned uranium mines affect inflammation and immune health in Native American adults living nearby.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of New Mexico Health Scis Ctr NIH-funded
Lab location1 site (Albuquerque, United States)
Project IDNIH-11124905 on NIH RePORTER

What this research studies

Researchers are working with partnering Native American communities in the Southwest to measure metals in people’s bodies and nearby environments. They will test blood and other biosamples for signs of oxidative stress, inflammation, and immune changes that may link to metal mixtures. The team will combine community-based sampling, laboratory analyses, and local input to identify which metals or combinations are most harmful. They will also explore whether specific dietary strategies could reduce those harmful effects.

Who could benefit from this research

Good fit: Ideal participants are adults (21+) from the partnering Native American tribal lands or nearby communities who may have environmental exposure to uranium and other metals.

Not a fit: People without measurable metal exposure, children under 21, or those living far from the affected tribal lands are unlikely to directly benefit from this project.

Why it matters

Potential benefit: If successful, this could point to specific metals driving health risks and practical diet-based steps to lower inflammation and disease risk in exposed communities.

How similar studies have performed: Previous biomonitoring has shown elevated metal levels in these communities and other studies link metals to oxidative stress and disease, but testing real-world metal mixtures and dietary mitigation is relatively new.

Where this research is happening

Albuquerque, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Atherosclerotic Cardiovascular DiseaseAutoimmune Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.