Genomic data resource to accelerate pediatric disease research
Official title: GMKF competing renewal
Funded at Broad Institute, INC. · NIH-11543096 · Data updated 2026-11-12
This grant helps a big research center generate and share high-quality genome and RNA data from children with diseases and their families to speed discoveries that can help young patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Broad Institute, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project start | September 1, 2026 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $6,978,514 |
| NIH project number | 3U24HD090743-09S2 |
| Project ID | NIH-11543096 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children with diagnosed diseases (and their families) who contribute samples for whole genome and RNA sequencing datasets.
✕Less likely to help
Children not contributing samples or not part of the specific data resource may not benefit directly.
What this research studies
The project expands a pediatric genomic data resource by producing and processing whole genome and RNA sequencing data from well-characterized patients and families. It focuses on collecting data and making it accessible to researchers in a user-friendly way, while integrating genetic information with detailed clinical data. The center leverages its expertise in high-throughput data generation, analysis, and disease gene discovery, and collaborates with investigators to meet their data needs. By comparing pediatric data to other large resources, it aims to improve variant interpretation and gene discovery relevant to child health.
Why it matters
Potential benefit: In the long run, this work could accelerate discovery of genetic causes of pediatric diseases and improve precision approaches for diagnosis and care.
How similar studies have gone: Prior pediatric genomics efforts have shown meaningful gains in gene discovery and variant interpretation through large, well-phenotyped data resources.
Where this research is happening
-
Broad Institute, INC.
Cambridge, United States Active
Researchers
- Principal investigator: Gabriel, Stacey — Broad Institute, INC.
- Study coordinator: Gabriel, Stacey
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.