Finding ways to lower heart disease risk in people with PTSD

Identifying Early Intervention Targets for Reducing Cardiovascular Risk in Posttraumatic Stress

NIH-funded research University of California Los Angeles · NIH-10453467

This study is looking at how PTSD might increase the chances of heart problems, especially by focusing on early signs of heart issues, and it aims to help improve treatments for people with PTSD to keep their hearts healthier.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-10453467 on NIH RePORTER

What this research studies

This research investigates how posttraumatic stress disorder (PTSD) affects the risk of developing cardiovascular disease (CVD). It aims to identify specific aspects of PTSD that contribute to early signs of heart problems, particularly focusing on endothelial dysfunction, which is a key precursor to CVD. By understanding these connections, the research seeks to inform better treatment strategies that could reduce cardiovascular risks in individuals with PTSD. The study will involve a diverse group of participants to ensure the findings are applicable to the general population.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who have experienced trauma and are diagnosed with PTSD.

Not a fit: Patients who do not have PTSD or have not experienced trauma may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing heart disease in individuals suffering from PTSD.

How similar studies have performed: While some studies have explored the link between PTSD and cardiovascular health, this research aims to expand on those findings with a broader and more nuanced approach.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Atherosclerotic Cardiovascular Diseaseatherosclerotic diseaseatherosclerotic vascular diseaseMental disordersMental health disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.