NIH-funded research NIH-funded research

Feasibility of a 12-week manualized music program to help cognition in older adults at risk for Alzheimer’s

Official title: Feasibility of Randomized Manualized Music Training Program as a Cognitive Intervention for Older Adults at High Risk of Alzheimer's Disease and Related Dementias

Funded at University of Maine Orono · NIH-11116599 · Data updated 2026-11-12

A 12-week, hands-on music program is being tested to see if it can help thinking skills in older adults who are at risk for Alzheimer’s disease and related dementias.

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Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Maine Orono
NIH-funded
Lab location1 site (Orono, United States)
Project startSeptember 18, 2026
Project endAugust 31, 2029
Funding year2026
Award (this year)$180,582
NIH project number1R34AG093142-01
Project IDNIH-11116599 on NIH RePORTER

Who could benefit from this research

Could help

Older adults at risk for Alzheimer’s disease and related dementias who can participate in a 12-week music training program.

Less likely to help

Individuals unable to participate in a 12-week program or with medical conditions interfering with participation may receive no benefit.

What this research studies

This project tests a practical, 12-week, manualized music training program designed for older adults at risk of cognitive decline. It builds on community input and prior work to measure feasibility and how well the program is received, with attention to how easy it would be to run in real communities. The study will look at changes in global cognition and executive function after the intervention, using rigorous methods to enhance reproducibility. Results from a pilot suggested the approach is acceptable and may improve cognitive outcomes, guiding future larger trials.

Why it matters

Potential benefit: If successful, the program could become a low-cost, engaging option to help maintain thinking skills in people at risk for dementia.

How similar studies have gone: Preliminary data from a pilot study indicated acceptability and potential cognitive benefits, supporting further rigorous testing.

Where this research is happening

  • University of Maine Orono
    Orono, United States
    Active

Researchers

  • Principal investigator: Macaulay, Rebecca — University of Maine Orono
  • Study coordinator: Macaulay, Rebecca

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.