Exploring the role of biological barriers in various diseases
Official title: Administrative Core
Funded at University of Rochester · NIH-11005754 · Data updated 2026-11-12
This study is looking at how certain tools can help us understand how diseases affect tissues in the body, with the goal of finding better treatments for conditions like autoimmune and central nervous system diseases, so patients can feel better and have more options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | January 15, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $153,602 |
| NIH project number | 5U2CAG088071-02 |
| Project ID | NIH-11005754 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals suffering from autoimmune conditions or central nervous system disorders.
✕Less likely to help
Patients with unrelated health conditions or those not affected by autoimmune or CNS diseases may not benefit from this research.
What this research studies
This research focuses on validating and qualifying Drug Development Tools (DDTs) that investigate how biological barriers affect the pathology of tissues in different diseases. The project is a collaboration between the University of Rochester and Duke University, involving a diverse team of experts. It aims to enhance data management and integration to support the development of new treatments. Patients may benefit from improved understanding and therapies for autoimmune and central nervous system diseases.
Why it matters
Potential benefit: If successful, this research could lead to better-targeted therapies for autoimmune and central nervous system diseases.
How similar studies have gone: Other research has shown success in using similar approaches to understand biological barriers in disease contexts, indicating a promising avenue for further exploration.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Mcgrath, James L — University of Rochester
- Study coordinator: Mcgrath, James L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.