Exploring the role of biological barriers in various diseases

Administrative Core

NIH-funded research University of Rochester · NIH-11005754

This study is looking at how certain tools can help us understand how diseases affect tissues in the body, with the goal of finding better treatments for conditions like autoimmune and central nervous system diseases, so patients can feel better and have more options.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-11005754 on NIH RePORTER

What this research studies

This research focuses on validating and qualifying Drug Development Tools (DDTs) that investigate how biological barriers affect the pathology of tissues in different diseases. The project is a collaboration between the University of Rochester and Duke University, involving a diverse team of experts. It aims to enhance data management and integration to support the development of new treatments. Patients may benefit from improved understanding and therapies for autoimmune and central nervous system diseases.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals suffering from autoimmune conditions or central nervous system disorders.

Not a fit: Patients with unrelated health conditions or those not affected by autoimmune or CNS diseases may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better-targeted therapies for autoimmune and central nervous system diseases.

How similar studies have performed: Other research has shown success in using similar approaches to understand biological barriers in disease contexts, indicating a promising avenue for further exploration.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autoimmune Diseasesautoimmune disorderautoimmunity diseaseBone InfectionCentral Nervous System Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.