Exploring non-invasive brain stimulation to improve cognitive function after stroke

Non-invasive brain stimulation and neurovascular mechanisms of post-stroke cognitive impairment

NIH-funded research University of Oklahoma Hlth Sciences Ctr · NIH-10949705

This study is looking at how a gentle electrical stimulation on the scalp might help stroke survivors who have trouble with thinking and memory, to see if it can boost their brain function and improve their daily lives.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Oklahoma Hlth Sciences Ctr NIH-funded
Lab location1 site (Oklahoma City, United States)
Project IDNIH-10949705 on NIH RePORTER

What this research studies

This research investigates the use of transcranial direct current stimulation (tDCS), a non-invasive technique that delivers a weak electrical current to the scalp, to enhance cognitive function in stroke survivors experiencing post-stroke cognitive impairment (PSCI). The study aims to understand how tDCS affects brain activity and blood flow, which could lead to new treatment options for improving cognitive abilities in these patients. By focusing on the neurovascular mechanisms involved, the research seeks to uncover the broader effects of brain stimulation beyond just neuronal activity. Participants may receive tDCS sessions as part of the intervention to assess its efficacy in improving cognitive outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are stroke survivors who are experiencing cognitive impairment within the first year after their stroke.

Not a fit: Patients who have not experienced a stroke or those with cognitive impairment due to other causes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a novel treatment option to enhance cognitive function in stroke survivors, potentially improving their quality of life and independence.

How similar studies have performed: Previous studies have shown promise in using tDCS for cognitive improvement in stroke patients, indicating that this approach has potential based on existing research.

Where this research is happening

Oklahoma City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.