NIH-funded research R01 grant

Exploring how inflammation affects human aggression

Official title: Inflammatory Challenge in Human Aggression

Funded at Ohio State University · NIH-11233543 · Data updated 2026-11-12

This study is looking at how inflammation in the body might affect how we act and feel, especially when it comes to aggressive behavior, and it's for anyone interested in understanding more about what drives aggression and its causes.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startJanuary 16, 2025
Project endMarch 31, 2029
Funding year2025
Award (this year)$65,363
NIH project number3R01MH133925-01A1S1
Project IDNIH-11233543 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation would include individuals who experience issues with aggression or related behavioral challenges.

Less likely to help

Patients who do not exhibit aggressive behavior or have no history of related issues may not benefit from this research.

What this research studies

This research investigates the relationship between inflammatory responses and aggressive behavior in humans. By examining how inflammation can influence emotional and behavioral responses, the study aims to uncover potential biological mechanisms behind aggression. Participants may undergo assessments and tests to measure inflammatory markers and behavioral responses, providing insights into how these factors interact. The findings could lead to a better understanding of aggression and its underlying causes.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for managing aggression and improving mental health treatments.

How similar studies have gone: Previous research has shown promising results in understanding the links between inflammation and behavior, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Coccaro, Emil Frank — Ohio State University
  • Study coordinator: Coccaro, Emil Frank

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.