Exploring how different bacteria grow and function
Official title: Quantitative Systemic Studies of Bacterial Physiology
Funded at University of California, San Diego · NIH-11014437 · Data updated 2026-11-12
This study is looking at how different types of bacteria, not just E. coli, grow and behave in various situations, using special techniques to help us understand them better, which could lead to improved ways to treat bacterial infections.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | March 1, 2024 |
| Project end | February 28, 2029 |
| Funding year | 2025 |
| Award (this year) | $544,515 |
| NIH project number | 5R35GM152133-02 |
| Project ID | NIH-11014437 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with infections caused by the studied bacterial species, such as E. coli, Pseudomonas, or Mycobacterium, would be ideal candidates to benefit from this research.
✕Less likely to help
Patients with infections caused by bacteria not included in this research, or those with viral or fungal infections, may not receive any benefit.
What this research studies
This research investigates the physiology of various bacterial species, moving beyond just E. coli to include others like Vibrio, Pseudomonas, and Mycobacterium. By using advanced techniques such as transcriptomics, proteomics, and metabolomics, the study aims to measure and compare the growth and metabolic processes of these bacteria under different conditions. The goal is to create detailed models that explain how these bacteria function at a molecular level, which could lead to better understanding and treatment of bacterial infections.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing bacterial infections and enhancing antibiotic effectiveness.
How similar studies have gone: Previous research has shown success in understanding bacterial physiology using similar approaches, particularly with E. coli, indicating a promising potential for this expanded study.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Hwa, Terence — University of California, San Diego
- Study coordinator: Hwa, Terence
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.