Exploring how dietary components affect COPD flare-ups
Official title: Methods for Unraveling the Impact of Dietary Xenobiotics on COPD Exacerbations with Multi-Dimensional Networks
Funded at Brigham and Women's Hospital · NIH-11059900 · Data updated 2026-11-12
This study is looking at how certain foods might affect flare-ups of COPD, and it's for people with the condition who want to help researchers learn more about the connection between diet and their breathing health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | April 1, 2024 |
| Project end | January 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $160,949 |
| NIH project number | 5K25HL173665-02 |
| Project ID | NIH-11059900 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with chronic obstructive pulmonary disease (COPD), particularly smokers and former smokers.
✕Less likely to help
Patients without a diagnosis of COPD or those who do not consume a varied diet may not benefit from this research.
What this research studies
This research investigates the relationship between dietary xenobiotics—small molecules derived from food—and acute exacerbations of chronic obstructive pulmonary disease (COPD). By utilizing advanced machine learning and network science methods, the study aims to analyze multi-omics data from patients with COPD to identify dietary factors that may influence the frequency and severity of COPD flare-ups. Participants will be involved in providing clinical and molecular data, which will help researchers understand how diet impacts their condition over time.
Why it matters
Potential benefit: If successful, this research could lead to dietary recommendations that help reduce the frequency and severity of COPD exacerbations.
How similar studies have gone: Previous research has shown promising results in understanding the impact of diet on chronic diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Menichetti, Giulia — Brigham and Women's Hospital
- Study coordinator: Menichetti, Giulia
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.