Exploring how aging factors like protein changes and nutrient sensing affect health.
Investigating the interplay between hallmarks of aging; protein glycation, nutrient sensing, and senescence
This study is looking at how certain changes in our bodies as we get older, like how proteins behave and how our cells respond to nutrients, can lead to health issues like insulin resistance, helping us find better ways to manage age-related problems.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Buck Institute for Research on Aging NIH-funded |
| Lab location | 1 site (Novato, United States) |
| Project ID | NIH-10901045 on NIH RePORTER |
What this research studies
This research investigates the connections between three key aspects of aging: protein glycation, nutrient sensing, and cellular senescence. It aims to understand how these factors interact and contribute to age-related diseases, particularly focusing on insulin resistance and its effects on bodily functions. By examining these relationships, the study seeks to uncover how aging impacts different tissues in the body, which could lead to new insights into managing age-related health issues. Patients may benefit from a better understanding of how these processes affect their health as they age.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults experiencing age-related health issues, particularly those with insulin resistance or metabolic disorders.
Not a fit: Patients who are younger and do not have any signs of age-related diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating age-related diseases, improving overall health in older adults.
How similar studies have performed: Previous research has shown promising results in understanding the role of aging hallmarks in health, suggesting that this approach could yield valuable insights.
Where this research is happening
Novato, United States
- Buck Institute for Research on Aging — Novato, United States (Active)
Researchers
- Principal investigator: Kapahi, Pankaj — Buck Institute for Research on Aging
- Study coordinator: Kapahi, Pankaj
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.