Exploring how a specific protein affects communication between brain cells and memory.
Official title: Investigating a novel form of intercellular synaptic plasticity
Funded at University of Utah · NIH-11001755 · Data updated 2026-11-12
This study is looking at a protein called Arc that helps brain cells talk to each other, which is important for learning and memory, and it's for anyone interested in how our brains work and what might go wrong in conditions like Alzheimer's or other memory issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $39,974 |
| NIH project number | 1F99NS139545-01 |
| Project ID | NIH-11001755 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with neurological disorders that affect memory and learning.
✕Less likely to help
Patients with no neurological conditions or those not experiencing memory issues may not benefit from this research.
What this research studies
This research investigates the role of a protein called Arc in the communication between neurons, which is crucial for learning and memory. By examining how Arc is released from neurons and its effects on other cells, the study aims to uncover new mechanisms of synaptic plasticity, which is the ability of synapses to strengthen or weaken over time. The research utilizes advanced techniques like 2-photon microscopy to observe these processes in real-time. Understanding these mechanisms could provide insights into how memory formation occurs and what goes wrong in neurological disorders.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating memory-related disorders and improving cognitive function.
How similar studies have gone: While the specific approach of investigating Arc's role in intercellular communication is novel, similar studies have shown promise in understanding synaptic mechanisms related to memory.
Where this research is happening
-
University of Utah
Salt Lake City, United States Active
Researchers
- Principal investigator: Sullivan, Kaelan Reinaldo — University of Utah
- Study coordinator: Sullivan, Kaelan Reinaldo
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.