Understanding how cells respond to changes in membrane tension
Official title: Plasma membrane stress response
Funded at University of Utah · NIH-11311762 · Data updated 2026-11-12
This study looks at how yeast cells react when their outer layer gets stretched or squeezed due to changes in their environment, helping us understand how they stay healthy and function properly.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $39,844 |
| NIH project number | 3R01GM152758-01S1 |
| Project ID | NIH-11311762 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research would include individuals with conditions that affect cellular stress responses or membrane integrity.
✕Less likely to help
Patients with stable conditions that do not involve cellular stress or membrane tension issues may not benefit from this research.
What this research studies
This research investigates how cells, particularly yeast, respond to changes in membrane tension caused by environmental factors. It focuses on the mechanisms that allow cells to sense and adapt to these changes, which are crucial for maintaining cell integrity and function. By studying the effects of osmotic stress on yeast, the research aims to uncover the role of specific cellular structures in managing membrane tension. This could provide insights into broader cellular processes that are important for various biological functions.
Why it matters
Potential benefit: If successful, this research could lead to advancements in understanding cellular stress responses, potentially impacting treatments for conditions related to cell dysfunction.
How similar studies have gone: Other research has shown success in understanding cellular responses to stress, but this specific approach focusing on membrane tension in yeast is relatively novel.
Where this research is happening
-
University of Utah
Salt Lake City, United States Active
Researchers
- Principal investigator: Babst, Markus — University of Utah
- Study coordinator: Babst, Markus
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.