Enhancing brain metastases care with clear AI insights
Official title: Enhancing precision medicine for brain metastases using interpretable and integrative deep learning
Funded at Massachusetts General Hospital · NIH-11332763 · Data updated 2026-11-12
A physician-scientist at MGH will use interpretable deep learning to understand why brain metastases resist treatment and how to tailor therapy for patients.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 1, 2025 |
| Project end | July 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $193,856 |
| NIH project number | 5K08EB037077-02 |
| Project ID | NIH-11332763 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with brain metastases or solid tumors under treatment who may benefit from personalized therapy approaches.
✕Less likely to help
Patients without access to the necessary imaging/genomic data or those not eligible for the targeted therapies being studied.
What this research studies
This grant supports a clinician who wants to move toward independent work by combining cancer genomics, imaging, and deep learning to personalize treatment for brain metastases. The project emphasizes translational work, mentorship from leaders in DL, and collaboration with top institutions to apply AI to real patient data. The goal is to generate clinically meaningful insights that could guide therapies for cancer patients with brain metastases. Training focus includes building practical DL skills and integrating multi-modal clinical information to inform decisions. The work will stay closely connected to patient care and early-phase clinical trial insights at MGH and affiliated centers.
Why it matters
Potential benefit: If successful, patients with brain metastases could receive more personalized and effective treatment strategies guided by AI-derived patterns.
How similar studies have gone: Prior work in DL for cancer has shown promise, but this project aims to advance interpretable methods and direct clinical applicability in brain metastases.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Kim, Albert — Massachusetts General Hospital
- Study coordinator: Kim, Albert
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.