Enalapril to protect heart health after preeclampsia
Official title: Enalapril for Cardiovascular Protection after Preeclampsia
Funded at Women and Infants Hospital-Rhode Island · NIH-11353560 · Data updated 2026-11-12
A small study will test whether enalapril can help protect the heart and blood vessels of women after preeclampsia.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Women and Infants Hospital-Rhode Island NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project start | July 15, 2026 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $244,569 |
| NIH project number | 1R03HL185269-01 |
| Project ID | NIH-11353560 on NIH RePORTER |
Who could benefit from this research
✓Could help
Women who recently had preeclampsia and are in the institution's remote blood pressure program may be eligible.
✕Less likely to help
Women not in the remote BP program or who have contraindications to ACE inhibitors may not benefit.
What this research studies
This project aims to see if adding enalapril after a preeclampsia-affected pregnancy can improve cardiovascular recovery beyond blood pressure control. It will enroll women in a postpartum remote BP management program and randomly assign them to receive enalapril versus standard care. The study will collect key health data to plan a larger future trial focused on long-term heart health after preeclampsia. If feasible, results could pave the way for new postpartum treatments to reduce future cardiovascular risk.
Why it matters
Potential benefit: If successful, enalapril could become part of postpartum care to lower future cardiovascular risk for women who had preeclampsia.
How similar studies have gone: Previous work suggests ACE inhibitors can provide cardioprotection, but this exact postpartum post-preeclampsia context is being explored.
Where this research is happening
-
Women and Infants Hospital-Rhode Island
Providence, United States Active
Researchers
- Principal investigator: Hauspurg, Alisse — Women and Infants Hospital-Rhode Island
- Study coordinator: Hauspurg, Alisse
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.